Table 6.
Pooled mean estimates of 6-min walk test (6MWT).a
| Population | All studies |
Only studies in which percent predicted could be calculated |
|
|---|---|---|---|
| Pooled estimate (m) | Pooled estimate (m) | Pooled percent predicted (%) | |
| Allb | |||
| Number of study populations | 23 | 13 | 13 |
| Outcome (95% CI) | 431.5 (390.4–472.6) | 440.5 (395.2–485.8) | 78.9 (69.2–90.0) |
| Prediction interval | 220.2 to 642.8 | 253.5 to 627.4 | 45.8 to 100.0 |
| I2 | 99.4% | 99.0% | 98.9% |
| MDR-TB or DR-TB | |||
| Number of study populations | 7 | 3 | 3 |
| Outcome (95% CI) | 372.4 (270.7–474.1) | 403.0 (294.2–511.7) | 70.5 (49.9–99.6) |
| Prediction interval | 0.0 to 747.4 | – | – |
| I2 | 99.6% | 95.1% | 97.6% |
| Only DS-TB | |||
| Number of study populations | 10 | 5 | 5 |
| Outcome (95% CI) | 465.2 (422.7–507.7) | 474.6 (396–553.3) | 84.3 (70.8–100.3) |
| Prediction interval | 303.8 to 626.6 | 166.0 to 783.3 | 42.6 to 100.0 |
| I2 | 99.2% | 99.6% | 99.4% |
Pooled estimates included all persons at risk for disability (I.e., all persons post-TB who underwent 6MWT).
“-“ Denotes prediction interval was not able to be estimated.
TB, tuberculosis; MDR-TB, multidrug-resistant tuberculosis; DS-TB, drug sensitive tuberculosis; EOT, end of treatment; m, metres; CI, confidence interval.
a
6MWT was measured at end of treatment or after treatment completion.
b
Includes both MDR-TB and DS-TB studies, and studies that either reported mixed populations (MDR and DS). Note also that some studies reported 6MWT results for multiple cohorts.