Table 7.
Incidence of complications: Pooled estimates of incidence of complications after successful TB treatment.
| Population | Outcome | n | Cavitation | Fibrosis | Bronchiectasis | Aspergilloma |
|---|---|---|---|---|---|---|
| TB | Number of study populations | 5 | 11 | 5 | 7 | 4 |
| Proportion of participants (n/N) | 680/32,951 | 438/1479 | 402/1403 | 423/2547 | 32/1710 | |
| Pooled estimate (95% CI) | 2.1% (1.2%–3.9%) | 31.4% (18.6%–47.7%) | 37.4% (21.0%–57.5%) | 16.8% (5.1%–43.4%) | 1.9% (0.9%–4.1%) | |
| I2 | 98.1% | 93.4% | 98.3% | 98.9% | 82.9% | |
| Prediction interval | 0.2%–19.8% | 3.0%–87.0% | 2.4%–93.6% | 0.2%–96.4% | 0.1%–39.9% |
Pooled estimates included all persons at risk for complications (I.e., the denominator in these estimates was all persons post-TB in the studies reporting on post-TB complications).
TB, tuberculosis; CI, confidence interval.