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. 2023 May 8;59:101979. doi: 10.1016/j.eclinm.2023.101979

Table 8.

Incidence of complications: Pooled estimates of incidence of lung cancer after successful TB treatment in studies also reporting incidence in non-TB controls.

Population Number of study populations Proportion of participants with lung cancer (n/N) Lung cancer per 1000 PY (95% CI) Incidence rate ratio (95% CI) Incidence Rate Difference per 1000 PY (95% CI)
TB 4 290/89,429 3.9 (2.5–6)a 4 (2.1–7.6) 2.7 (1.2–4.2)
Controls 4 3197/7,288,122 1 (0.4–2.4)b NA NA

Pooled estimates included all persons at risk for complications (I.e., the denominator in these estimates was all persons post-TB in the studies reporting on post-TB complications).

TB, tuberculosis; PY, person-years; CI, confidence interval; NA, not applicable.

a

Prediction interval: 0.49 to 30.64, I2 = 92.3%.

b

Prediction interval: 0 to 7.4, I2 = 99.9%.