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. 2022 Dec 1;8(3):e10460. doi: 10.1002/btm2.10460

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© 2022 The Authors. Bioengineering & Translational Medicine published by Wiley Periodicals LLC on behalf of American Institute of Chemical Engineers.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Inhibition of the RIR‐induced activation of retinal gliocytes and inflammatory cytokine secretion by Que@TPP‐ROS‐Lips following intravitreal injection. Representative CLSM images showing the levels of GFAP (a) and IBA1 (b) in retinal cryosections collected at 7 days after injection. Fluorescence intensities of GFAP (c) and IBA1 (d) quantified by ImageJ software (scale bar = 50 μm; n = 6; *p < 0.05 compared with the saline group). Levels of TNF‐α (e) and IL‐1β (f) determined by the ELISA. The results represent mean ± SD of fold change (scale bar = 50 μm; n = 6; *p < 0.05 compared with the saline group).