Table 1.
Discontinuation n = 76 | Continuation n = 95 | P Value | |
---|---|---|---|
Mean age (SD) | 71 (±11.7) | 71 (±12.1) | .92 |
Mean symptom onset history in days (SD) | 6 (±4.4) | 6 (±4.7) | .94 |
Mean antiplatelet days (SD) | 1.4 (±2.9) | 8.1 (±5.1) | <.05 |
Male sex (%) | 40 (53) | 57 (60) | .42 |
Race (%) | <.05 | ||
Black | 42 (55) | 35 (37) | <.05 |
White | 20 (26) | 39 (41) | .06 |
Other | 14 (18) | 21 (22) | .69 |
Preadmission antiplatelet regimen (%) | .68 | ||
Aspirin | 59 (78) | 69 (73) | .57 |
Clopidogrel | 6 (8) | 13 (14) | .34 |
Aspirin + clopidogrel | 9 (12) | 10 (11) | .98 |
Other | 2 (3) | 3 (3) | 1 |
Death while DNR and/or DNI (%) | 23 (30) | 10 (11) | <.05 |
Admission from long-term care facility (%) | 23 (30) | 22 (23) | .38 |
Oxygen supplementation prior to admission (%) | 2 (3) | 4 (4) | .69 |
Any hydroxychloroquine during admission (%) | 59 (78) | 85 (89) | .06 |
Any Tocilizumab during admission (%) | 8 (11) | 6 (6) | .48 |
Any anticoagulation ≥50% of admission (%) | 59 (78) | 81 (85) | .28 |
Any therapeutic anticoagulation | 13 (17) | 13 (14) | .68 |
Any prophylactic anticoagulation | 54 (71) | 74 (78) | .40 |
Any corticosteroid during admission (%) | 23 (30) | 22 (23) | .38 |
Initial white blood cell value (IQR) | 6.9 (5.4–9.8) n = 75 | 6.2 (4.8–8.1) n = 95 | .08 |
Initial hemoglobin value (IQR) | 12.6 (10.3–14) n = 75 | 12.6 (11.4–14.1) n = 95 | .36 |
Initial hematocrit value (IQR) | 39.4 (32–43.1) n = 75 | 38.4 (35–43.1) n = 95 | .55 |
Initial platelet value (IQR) | 181 (148–251) n = 75 | 198 (148–275) n = 95 | .28 |
PT in first 48 hours of admission (IQR) | 14.3 (13.4–15.4) n = 24 | 12.8 (12.4–13.9) n = 11 | <.05 |
PTT in first 48 hours of admission (IQR) | 29.7 (29.1–32.4) n = 20 | 30.1 (27.3–31.6) n = 8 | .78 |
INR in first 48 hours of admission (IQR) | 1.3 (1.2–1.4) n = 25 | 1.1 (1.1–1.2) n = 13 | <.05 |
D-dimer in first 48 hours of admission (IQR) | 731 (17–714) n = 24 | 439 (72–538) n = 28 | .13 |
Fibrinogen in first 48 hours of admission (IQR) | 700 (643–700) n = 21 | 662 (552–700) n = 6 | .25 |
SD, standard deviation; DNR, do not resuscitate; DNI, do not intubate; IQR, interquartile range.