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. Author manuscript; available in PMC: 2023 Nov 1.
Published in final edited form as: Nat Med. 2022 Oct 17;28(11):2424–2435. doi: 10.1038/s41591-022-02023-7

Extended Data Fig. 6. Effect of RMD on transcriptionally (mRNA+) and transcriptionally + translationally (mRNA+p24+) active HIV-1-infected cells.

Extended Data Fig. 6

Data are shown as in Fig. 3f-g. Individual and overall median fold change (column) from pre- to post-RMD infusions in groups ART+RMD (n=8) and ART+3BNC117+RMD (n=10) on CD3+CD8− T cells expressing HIV-1 mRNA (a) or mRNA and Gag p24 (b). P values comparing within group was calculated using paired two-tailed Wilcoxon test. Due to a faulty mRNA probe in the 2nd batch of fluorescence in situ hybridization-flow cytometry analyses, mRNA data was only available for half of the study population.

ART, antiretroviral therapy; RMD, romidepsin.