Table II.
AASLD and EASL recommendations regarding COVID-19 vaccination for patients with chronic liver disease and liver transplant recipients.
Type of vaccine | Vaccine | Administration | Booster dose | Population |
---|---|---|---|---|
mRNA-based | mRNA-1273 (Moderna) | Three doses | Bivalent ≥2 months after primary series | Age, ≥6 months (Pfizer-BioNTech bivalent booster recommended for ages 12-17 years; Moderna or Pfizer-BioNTech bivalent booster recommended for ages ≥18 years) |
BNT162b2 (BioNTech and Pfizer) vaccine | Three doses | Bivalent ≥2 months after primary series | Age, ≥6 months (Pfizer-BioNTech bivalent booster recommended for ages 12-17 years; Moderna or Pfizer-BioNTech bivalent booster recommended for ages ≥18 years) | |
Adenovirus vector-based | Ad26.COV2-S vaccine (Johnson & Johnson) | Single dose followed by mRNA vaccine | Bivalent ≥2 months after primary series | Age, ≥18 years (mRNA primary vaccine series preferred whenever possible) |
Protein subunit vaccines | Novavax (NVX-CoV2373) | Two doses | Bivalent ≥2 months after primary series | Age, ≥12 years |
AASLD, American Association for the Study of Liver Diseases; EASL, European Association for the Study of the Liver; COVID-19, coronavirus disease 2019.