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. 2023 May 3;25(6):291. doi: 10.3892/etm.2023.11990

Table II.

AASLD and EASL recommendations regarding COVID-19 vaccination for patients with chronic liver disease and liver transplant recipients.

Type of vaccine Vaccine Administration Booster dose Population
mRNA-based mRNA-1273 (Moderna) Three doses Bivalent ≥2 months after primary series Age, ≥6 months (Pfizer-BioNTech bivalent booster recommended for ages 12-17 years; Moderna or Pfizer-BioNTech bivalent booster recommended for ages ≥18 years)
  BNT162b2 (BioNTech and Pfizer) vaccine Three doses Bivalent ≥2 months after primary series Age, ≥6 months (Pfizer-BioNTech bivalent booster recommended for ages 12-17 years; Moderna or Pfizer-BioNTech bivalent booster recommended for ages ≥18 years)
Adenovirus vector-based Ad26.COV2-S vaccine (Johnson & Johnson) Single dose followed by mRNA vaccine Bivalent ≥2 months after primary series Age, ≥18 years (mRNA primary vaccine series preferred whenever possible)
Protein subunit vaccines Novavax (NVX-CoV2373) Two doses Bivalent ≥2 months after primary series Age, ≥12 years

AASLD, American Association for the Study of Liver Diseases; EASL, European Association for the Study of the Liver; COVID-19, coronavirus disease 2019.