Table 1.
Comparison of subjects at first follow-up visit by AMH shows AMH levels consistent with diminished ovarian reserve are an associated with age, taking HC and higher MCV.
|
AMH ≥ 1.1
(n=14) |
AMH < 1.1
(n=42) |
p-value** | |
|---|---|---|---|
| Age at enrollment, years | 24.5 (8.0) | 34.5 (9.0) | <0.0001 |
| Age at first follow-up visit, years | 29.1 (7.5) | 39.3 (8.1) | <0.0001* |
| Months after MSH enrollment to follow-up visit, months median(IQR) | 29.5 (8.75) | 31(6) | 0.35 |
| BMI, kg/m2, median (IQR) | 20.1 (2.1) | 21.3 (7.3) | 0.54 |
| Received HC in RCT, n(%) | 7 (50%) | 26 (62%) | 0.43 |
| Taking HC at time of sample, n(%) | 8 (57%) | 36 (86%) | 0.024* |
| Months HC exposure during RCT, median (IQR) | 11.0 (28.0) | 23.5(33.0) | 0.44 |
| ANC, K/mcL, median (IQR) | 4.7 (2.2) | 5.6 (3.8) | 0.75 |
| MCV, fL, median (IQR) | 95.8 (11.9) | 105.3 (14.3) | 0.03* |
p-value was calculated using Wilcoxon rank-sum test for continuous variables and Pearson Chi-Square test for categorical variables