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. 2023 May 17;21(5):e08006. doi: 10.2903/j.efsa.2023.8006

Table 10.

Summary of the outcome of studies on birth length in which exposure was used as categorical variable

Reference Study design Exposure Timing of exposure/assessment Com‐pound Unit Exposure high Exposure low n expos. high n expos. low n total Mean difference (cm) (95% CI) Ad‐justed
Shahraki et al. (2016) RCT Supple‐mentation From 4–16 gw onwards Pyridoxine HCl mg/day 40 Ondan‐setron 100 88 188 0.5 (0.07, 0.93) No
Schuster et al. (1984) RCT Supple‐mentation From 6–21 gw onwards Pyridoxine HCl mg/day 7.5–20 0–5 112 84 196 −0.2 (−0.88, 0.48) No
Chang (1999) CS Cord blood Birth PLP nmol/L ≥ 50 < 40 NR NR 209 2 (1.3, 2.7) No

CI: confidence interval; CS: cross‐sectional study; expos.: exposure; gw: gestational weeks; HCl: hydrochloride; NR: not reported; PLP: pyridoxal phosphate; RCT: randomised controlled trial.