Table 10.
Reference | Study design | Exposure | Timing of exposure/assessment | Com‐pound | Unit | Exposure high | Exposure low | n expos. high | n expos. low | n total | Mean difference (cm) (95% CI) | Ad‐justed |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Shahraki et al. (2016) | RCT | Supple‐mentation | From 4–16 gw onwards | Pyridoxine HCl | mg/day | 40 | Ondan‐setron | 100 | 88 | 188 | 0.5 (0.07, 0.93) | No |
Schuster et al. (1984) | RCT | Supple‐mentation | From 6–21 gw onwards | Pyridoxine HCl | mg/day | 7.5–20 | 0–5 | 112 | 84 | 196 | −0.2 (−0.88, 0.48) | No |
Chang (1999) | CS | Cord blood | Birth | PLP | nmol/L | ≥ 50 | < 40 | NR | NR | 209 | 2 (1.3, 2.7) | No |
CI: confidence interval; CS: cross‐sectional study; expos.: exposure; gw: gestational weeks; HCl: hydrochloride; NR: not reported; PLP: pyridoxal phosphate; RCT: randomised controlled trial.