Skip to main content
. 2023 May 17;21(5):e08006. doi: 10.2903/j.efsa.2023.8006
References Risk of bias domains (a) Tier (b)
Exposure KEY Outcome KEY Confounding KEY Inappropriate selection Attrition Other sources of bias/statistics
Bacharach et al. ( 2017 ) + + −− NA NA 2
Baer (1984) NR NR −− NA NA 3
Berger and Schaumburg (1984) NR + −− NA NA 2
Blackburn and Warren (2017) NR NR −− NA NA 3
Brush et al. ( 1988 ) −− −− −− NR −− 3
Chaudary et al. ( 2003 ) −− NR NR + 3
Chaudary and Cornblath (2013) + + −− NA NA 2
Dalton and Dalton (1987) + −− −− NR ++ 2
Dalton ( 1985 ) + NR −− NA NA −− 2
Falcone and Sowa (2013) + NR −− NA NA −− 2
Foca ( 1985 ) + + −− NA NA −− 2
Franzblau et al. ( 1996 ) + + NR NR + 2
Friedman et al. ( 1986 ) NR + −− NA NA 2
Gdynia et al. ( 2008 ) + + −− NA NA 2
Kaur et al. ( 2014 ) + + −− NA NA 2
Keniston et al. ( 1997 ) + + + + 2
Malek et al. ( 2020 ) + + −− NA NA 2
No authors listed ( 2009 ) NR NR −− NA NA −− 3
No authors listed ( 2020 ) NR NR −− NA NA −− 3
Parry and Bredesen (1985) NR −− NA NA −− 3
Schaumburg et al. ( 1982 ) NR + −− NA NA 2
Schaumburg et al. ( 1983 ) and No authors listed (1984) NR + −− NA NA 2
Scott et al. ( 2008 ) + + −− NA NA 2
Shrim et al. ( 2006 ) −− −− −− NR ++ 3
Stewart et al. ( 2022 ) + + + + + 1
van Hunsel et al. ( 2018 ) NR −− −− NA NA 3
Vasile et al. ( 1984 ) −− + −− NA NA 2
Visser et al. ( 2014 ) + + + ++ + 1
Vrolijk et al. ( 2020 ) −− −− NA NA −− 3
Waterston and Gilligan (1987) −− + −− NA NA 2
(a)

Expert judgement was translated into a rating scale for each question to be answered as follows: (++): definitely low RoB; (+): probably low RoB; (NR): not reported; (−): probably high RoB; (− −): definitively high RoB.

(b)

The individual rating for each question was combined by an algorithm and translated to an overall tier of reliability for each individual study (RoB tier 1: low RoB; RoB tier 2: moderate RoB; RoB tier 3: high RoB).