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. 2023 May 3;14:1085610. doi: 10.3389/fimmu.2023.1085610

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Copyright © 2023 Forte, Pellegrino, Trabanelli, Tonetti, Ricci, Cenerenti, Comai, Tazzari, Lazzarotto, Buratta, Urbanelli, Narimanfar, Alabed, Mecucci, La Manna, Emiliani, Jandus, Ranieri, Cavo, Catani and Palandri

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Comparison between EPs from COVID-19 patients (n=10) and HC (n=10) using MACSPlex exosome kit. Background-corrected median APC fluorescence intensity (MFI) for selected markers: (A) tetraspanins (CD9, CD63, CD81), (B–E) the only significantly different markers between COVID-19 patients and controls (CD326, CD19, CD24, ROR1). (F) Superimposed graph with background-corrected median APC fluorescence intensity normalized to exosome marker mean (CD9, CD63, CD81) for all 37 surface epitopes on the different purified EP preparations comparing patients and controls. *p<0.05, **p<0.01, ***p<0.001, ****p<0.001.