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. Author manuscript; available in PMC: 2024 Mar 1.
Published in final edited form as: J Med Virol. 2023 Mar;95(3):e28673. doi: 10.1002/jmv.28673

Figure 5.

Figure 5.

ELISA binding and cross-neutralization of RBD-reactive mAbs against Omicron subvariants. (A) Omicron BA.1 RBD ELISA. The OD at 450 nm (mean± SD, n= 4 replicates per mAb dilution) was plotted by nonlinear regression curve fit (Specific binding with Hill slope). Microneutralization against live infectious Omicron subvariants including (B) Omicron BA.1, (C) Omicron BA.1.1, (D) Omicron BA.2, (E) Omicron BA.4 and (F) Omicron BA.5. The % virus infection verse the wells that contained virus only (mean± SD, n= 8 replicates per mAb concentration) were plotted by 4-parameter logistic curve fitting. Estimated IC50 values of individual mAbs are summarized in Table 1.