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. 2023 May 17;22:39. doi: 10.1186/s12941-023-00587-x

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Genetic mutations in the 50 cephalosporin-DS N. gonorrhoeae strains from different regions. The vertical axis represents 50 cephalosporin-DS N. gonorrhoeae strains and their regional distribution, and the horizontal axis represents the characteristics of each strain, including ceftriaxone DS or cefixime DS and the genetic characteristics. Red represents the presence of cephalosporin DS or mutations (Yes), light pink represents no cephalosporin DS or no mutation, namely Wild Type (WT), and colorless represents NA with unknown information. a: A39T/G45D mutation in mtrR; b: D86/S87 mutation in parC; c: NEIS2213 (zeta_3 toxin variant); d: NEIS0013 (308 bp deletion); e: NEIS0408 (pilQ_S341N/N648S), f: NEIS1600 (parE); g: NEIS1609 (folP_R228S); h: NEIS2357 (TEM-1/TEM-135); h: NEIS2958 (54 bp deletion) mutations