Table 6. Comparison of side effects between only DFMO cycle vs. DFMO with etoposide in NCT01059071*.
*[40]
ALT: alanine transaminase; AST: aspartate transaminase; GGT: gamma glutamyl transferase; NR: not related
| Side Effect | DFMO only (n=21) | DFMO + etoposide (n=17) | OR | 95% CI | P-value |
| Anemia | 3 | 5 | 2.5 | 0.52-12.46 | 0.26 |
| Neutrophil count decrease | 2 | 7 | 6.65 | 1.15-38.19 | 0.03* |
| Platelet count decrease | 2 | 3 | 2.03 | 0.29-13.85 | 0.46 |
| White blood cell decrease | 0 | 1 | NR | NR | NR |
| ALT elevation | 1 | 1 | NR | NR | NR |
| Anorexia | 1 | 0 | NR | NR | NR |
| AST elevation | 1 | 2 | NR | NR | NR |
| Conjunctivitis | 1 | 0 | NR | NR | NR |
| Constipation | 1 | 1 | NR | NR | NR |
| Diarrhea | 1 | 0 | NR | NR | NR |
| GGT elevation | 1 | 0 | NR | NR | NR |
| Hypoalbuminemia | 1 | 0 | NR | NR | NR |
| Hypophosphatemia | 1 | 0 | NR | NR | NR |
| Infection, sinus | 0 | 1 | NR | NR | NR |
| Mouth pain | 0 | 1 | NR | NR | NR |
| Nausea | 0 | 1 | NR | NR | NR |
| Neuropathy | 0 | 1 | NR | NR | NR |
| Pain | 0 | 1 | NR | NR | NR |