Fig. (1).
Scheme of the meningeal lymphatic system in humans. Meningeal lymphatic vessels (MLVs) are situated within the dura mater and drain the cerebrospinal fluid (CSF) from the adjacent subarachnoid space, and the interstitial fluid (ISF) coming from the glymphatic system. This mixture (CSF-ISF) fluid is further transported by MLVs into deep cervical lymph nodes (dcLNs) via foramina at the base of the skull. Some lymph is also transported through the lymph vessels passing the cribriform plate with the olfactory nerves into superficial cervical lymph nodes (dcLNs). Figure adapted and modified from Tamura, R. Neurosurg Rev 2020, 43, 1055-1064.