Table 1.
Differences between meningeal lymphatic system and glymphatic system.
Parameter | Meningeal Lymphatic System | Glymphatic System |
localization | dura mater | brain interstitium |
structure | resemble lymphatic vessels from other organs, however, have also some characteristic features | perivascular astrocyte endfeet wall and brain interstitium |
forces of fluid movement | probably contractile activity of collecting mLVs wall (similarly as in lymphatic vessels in other organs) | dependent on arterial pressure, respiratory, sleep and position of head |
function | drainage of CSF from subarachnoid space, including venous sinuses to the deep cervical lymph nodes | CSF-ISF exchange in the brain parenchyma |
Abbreviations: CSF - cerebrospinal fluid; ISF - interstitial fluid; mLVs - meningeal lymphatic vessels.