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. 2023 Feb 1;21(2):380–391. doi: 10.2174/1570159X20666220411091332

Table 1.

Differences between meningeal lymphatic system and glymphatic system.

Parameter Meningeal Lymphatic System Glymphatic System
localization dura mater brain interstitium
structure resemble lymphatic vessels from other organs, however, have also some characteristic features perivascular astrocyte endfeet wall and brain interstitium
forces of fluid movement probably contractile activity of collecting mLVs wall (similarly as in lymphatic vessels in other organs) dependent on arterial pressure, respiratory, sleep and position of head
function drainage of CSF from subarachnoid space, including venous sinuses to the deep cervical lymph nodes CSF-ISF exchange in the brain parenchyma

Abbreviations: CSF - cerebrospinal fluid; ISF - interstitial fluid; mLVs - meningeal lymphatic vessels.