FIGURE 2.

The bioactive glass (BG)/sodium alginate (SA) composite hydrogels modulated the inflammatory responses for efficient skin regeneration. (A) FACS results of RAW cells cultured with normal medium (control) and BG‐containing composite hydrogel after 12 and 24 h. RAW cells were stained with iNOS (M1 marker) and ARG (M2 marker). The table showed the ratios of M1 and M2 phenotypes of the RAW cells. (B) Gross photographs of the skin wounds treated with BG/SA composite hydrogel and SA solution (without BG) in the normal mouse (Macrophage) and macrophage‐depleted mouse (Macrophage‐) at different points of time. Reproduced with permission.^{[ 39 ]} Copyright 2020, Elsevier