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. 2023 Jan 21;3(1):20210170. doi: 10.1002/EXP.20210170

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© 2023 The Authors. Exploration published by Henan University and John Wiley & Sons Australia, Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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NIR‐responsive separable microneedles containing BP quantum dots and oxygen‐carrier Hb for promoting wound healing. (A) Design and working mechanism of the microneedle patch. (B) Images of the skin wounds of different groups on days 0, 3, 5, 7, and 9 (scale bar: 0.5 cm). (C) Corresponding H&E staining of the wound beds on day 9 (scale bar: 500 µm). Quantitative analysis of the (D) granulation tissue width and (E) epithelial thickness on day 9. G1: control group, G2: BP microneedles group, G3: BP + Hb microneedles group, G4: BP + Hb + NIR microneedles group. Reproduced with permission.^[ ¹¹⁷ ^] Copyright 2020, American Chemical Society