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. 2023 Apr 5;3(2):20220115. doi: 10.1002/EXP.20220115

FIGURE 1.

FIGURE 1

The current toolbox of mitochondria‐targeting‐based reactive oxygen species (ROS) modulation (photodynamic therapy (PDT), chemodynamic therapy (CDT), sonodynamic therapy (SDT), radiodynamic therapy (RDT), photothermal therapy (PTT), starvation strategy, and the combination methods) for cancer treatment. Positively charged molecules (triphenylphosphonium (TPP), berberine (BBR)) and hydrophobic natural amino acid (phenylalanine, tyrosine, isoleucine) are presented as alternative sources to target mitochondria.