FIGURE 8.

(A‐i) The scheme of Q11H and Q11R co‐assembly to form amyloid‐like nanofibers. (A‐ii) Catalytic reaction rates for hydrolysis of pNPA vs molar ratio of Q11R to Q11H. Adapted with permission.^{[ 96 ]} Copyright 2014, The American Chemical Society. (B‐i) The pH‐switched artificial hydrolase based on conformational change of VK2H and the cartoon structure of the bilayer. (B‐ii) Catalytic rate of VK2H nanofibers at different pH versus the initial catalytic rate of VK2H fibrils at pH 9.5 and the on‐off switch of catalytic activity of VK2H peptide by a change in pH between 6.0 and 9.0. Adapted with permission.^{[ 97 ]} Copyright 2017, Wiley‐VCH