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Role of proline and lysine hydroxylation PTMs in the maturation and assembly of fibrillar collagen molecules. The schematic presents major steps in the processing of fibrillar collagens, with the prolyl and lysyl hydroxylases and schematized target residues in bold. See text for details. Adapted from Fig. 2B of Ref. 29, and reproduced under author’s permitted use of Portland Press. ER, endoplasmic reticulum; PTMs, posttranslational modifications.
