Table 2.
Post–Heart Transplantation Survival in Heart Transplantations From All COVID-19, Active COVID-19, and Recently Resolved COVID-19 Donors
| 6-Month Cumulative KM Survival Estimates, % (95% CI) |
1-Year Cumulative KM Survival Estimates, % (95% CI) |
Unadjusted and Adjusted 6-Month Mortality, Cox HR (95% CI) | Unadjusted and Adjusted 1-Year Mortality, Cox HR (95% CI) | |
|---|---|---|---|---|
| Non–COVID-19 donors (n = 5,641) | 93.0 (92.2-93.7) | 90.8 (89.9-91.6) | ||
| All COVID-19 donors (n = 239) | 88.2 (82.2-92.3) | 80.7 (70.5-87.7) | 1.55 (0.99-2.44); P = 0.054a | 1.74 (1.15-2.63); P = 0.008a |
| 1.61 (1.03-2.53); P = 0.038b | 1.81 (1.20-2.73); P = 0.005b | |||
| 1.62 (1.03-2.55); P = 0.036c | 1.83 (1.21-2.77); P = 0.004c | |||
| Active COVID-19 donors (n = 150) | 86.2 (77.6-91.6) | 76.8 (61.9-86.5) | 1.74 (1.02-2.96); P = 0.043a | 1.98 (1.22-3.22); P = 0.006a |
| 1.79 (1.05-3.07); P = 0.033b | 2.05 (1.26-3.34); P = 0.004b | |||
| 1.81 (1.07-3.11); P = 0.029c | 2.10 (1.29-3.42); P = 0.003c | |||
| Recently resolved COVID-19 donors (n = 89) | 91.5 (81.8-96.1) | 86.4 (69.5-94.3) | 1.26 (0.56-2.82); P = 0.579a | 1.43 (0.64-2.84); P = 0.439a |
| 1.31 (0.58-2.94); P = 0.511b | 1.41 (0.67-2.97); P = 0.372b | |||
| 1.30 (0.58-2.91); P = 0.525c | 1.40 (0.66-2.94); P = 0.371c |
KM = Kaplan-Meier; other abbreviations as in Table 1.
a
Unadjusted model.
b
Model adjusted for recipient age, sex, race (Black vs others), sex mismatch, size mismatch, ischemic origin, UNOS status, inotropic agent use, IABP, LVAD, ECMO status, and donor age, sex, DCD status, and total ischemic time >4 hours.
c
Model adjusted for recipient age, sex, race (Black vs others), sex mismatch, size mismatch, ischemic origin, blood group O, UNOS status, inotropic agent use, IABP, LVAD, ECMO status, and donor age, sex, DCD status, donor LVEF <50%, and cause of death.