Skip to main content
. Author manuscript; available in PMC: 2023 May 17.
Published in final edited form as: JACC Heart Fail. 2023 Feb;11(2):133–142. doi: 10.1016/j.jchf.2022.11.025

CENTRAL ILLUSTRATION.

CENTRAL ILLUSTRATION

Optimal Overall Strategy for Genetic Evaluation in Patients With Cardiomyopathy

Identification of the optimal proband, collection of family history, and pretest counseling are recommended prior to initiation of genetic testing. Genetic sequencing results are analyzed for presence of important variants, interpreted in the context of the proband’s phenotype. Patients and relatives are counseled as to clinical recommendations based on each variant. VUS = variant of uncertain significance.