Table 3. Cohort characteristics before propensity score matching (PSM), reflecting differing percentages of characteristics (demographics) with standardized mean differences (SMD) for those prescribed a specific statin compared to the control cohort not treated with a statin.
| Characteristic | No Statins | Atorvastatin | SMD | Lovastatin | SMD | Pitavastatin | SMD | Pravastatin | SMD | Rosuvastatin | SMD | Simvastatin | SMD |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | 65978 | 2676 | 70 | 13 | 383 | 404 | 784 | ||||||
| Age (mean (SD)) | 47.3 (18.5) | 67.6 (13.4) | -1.26 | 70.9 (11.5) | -1.54 | 69.3 (14.6) | -1.32 | 70.3 (11.9) | -1.48 | 67.4 (12.4) | -1.28 | 70.4 (13.1) | -1.44 |
| Age (%) | |||||||||||||
| 18–39 | 25902 (39.3) | 64 (2.4) | 1.02 | 0 (0.0) | 1.14 | 1 (7.7) | -0.80 | 5 (1.3) | 1.07 | 7 (1.7) | 1.05 | 15 (1.9) | 1.04 |
| 40–49 | 11601 (17.6) | 180 (6.7) | -0.34 | 4 (5.7) | -0.38 | 0 (0.0) | 0.65 | 15 (3.9) | -0.45 | 31 (7.7) | -0.30 | 47 (6.0) | -0.37 |
| 50–59 | 11289 (17.1) | 490 (18.3) | -0.03 | 8 (11.4) | 0.16 | 2 (15.4) | 0.05 | 48 (12.5) | 0.13 | 63 (15.6) | 0.04 | 90 (11.5) | 0.16 |
| 60–69 | 7987 (12.1) | 700 (26.2) | -0.36 | 19 (27.1) | -0.39 | 4 (30.8) | -0.47 | 97 (25.3) | -0.34 | 110 (27.2) | -0.39 | 189 (24.1) | -0.32 |
| 70–79 | 4948 (7.5) | 658 (24.6) | 0.48 | 21 (30.0) | 0.60 | 0 (0.0) | 0.40 | 129 (33.7) | 0.68 | 129 (31.9) | 0.65 | 222 (28.3) | 0.56 |
| 80+ | 4251 (6.4) | 584 (21.8) | 0.45 | 18 (25.7) | 0.54 | 6 (46.2) | 1.01 | 89 (23.2) | 0.49 | 64 (15.8) | 0.30 | 221 (28.2) | 0.60 |
| Sex (%) | |||||||||||||
| Female | 34842 (52.8) | 1284 (48.0) | 0.10 | 36 (51.4) | 0.03 | 7 (53.8) | -0.02 | 175 (45.7) | 0.14 | 191 (47.3) | 0.11 | 359 (45.8) | 0.14 |
| Male | 31136 (47.2) | 1392 (52.0) | -0.10 | 34 (48.6) | -0.03 | 6 (46.2) | 0.02 | 208 (54.3) | -0.14 | 213 (52.7) | -0.11 | 425 (54.2) | -0.14 |
| Race (%) | |||||||||||||
| American Indian or Alaska Native | 1425 (2.2) | 47 (1.8) | 0.03 | 0 (0.0) | 0.21 | 0 (0.0) | 0.21 | 5 (1.3) | 0.07 | 5 (1.2) | 0.07 | 11 (1.4) | 0.06 |
| Asian or Pacific Islander | 1461 (2.2) | 77 (2.9) | -0.04 | 5 (7.1) | -0.24 | 0 (0.0) | 0.21 | 11 (2.9) | -0.04 | 9 (2.2) | 0.00 | 34 (4.3) | -0.12 |
| Black or African American | 12631 (19.1) | 432 (16.1) | 0.08 | 13 (18.6) | 0.02 | 2 (15.4) | 0.10 | 102 (26.6) | -0.18 | 56 (13.9) | 0.14 | 131 (16.7) | 0.06 |
| Mixed Racial Group | 270 (0.4) | 9 (0.3) | 0.01 | 2 (2.9) | -0.19 | 0 (0.0) | 0.09 | 1 (0.3) | 0.03 | 0 (0.0) | 0.09 | 1 (0.1) | 0.05 |
| Other Racial Group | 9378 (14.2) | 271 (10.1) | 0.13 | 7 (10.0) | 0.13 | 0 (0.0) | 0.58 | 27 (7.0) | -0.23 | 26 (6.4) | -0.26 | 74 (9.4) | -0.15 |
| White | 40813 (61.9) | 1840 (68.8) | -0.15 | 43 (61.4) | 0.01 | 11 (84.6) | -0.53 | 237 (61.9) | <0.001 | 308 (76.2) | -0.32 | 533 (68.0) | -0.13 |
| Ethnicity (%) | |||||||||||||
| Hispanic or Latino | 30158 (45.7) | 1086 (40.6) | 0.10 | 18 (25.7) | 0.43 | 5 (38.5) | 0.15 | 105 (27.4) | 0.39 | 174 (43.1) | 0.05 | 297 (37.9) | 0.16 |
| Not Hispanic or Latino | 35820 (54.3) | 1590 (59.4) | -0.10 | 52 (74.3) | -0.43 | 8 (61.5) | -0.15 | 278 (72.6) | -0.39 | 230 (56.9) | -0.05 | 487 (62.1) | -0.16 |
| Encounter Type (%) | |||||||||||||
| Admitted for Observation | 2272 (3.4) | 176 (6.6) | -0.14 | 4 (5.7) | -0.11 | 0 (0.0) | 0.27 | 24 (6.3) | -0.13 | 28 (6.9) | -0.16 | 37 (4.7) | -0.07 |
| Emergency | 24603 (37.3) | 368 (13.8) | 1.03 | 12 (17.1) | 0.92 | 2 (15.4) | 0.98 | 53 (13.8) | 1.03 | 67 (16.6) | 0.94 | 90 (11.5) | -1.07 |
| Inpatient | 38087 (57.7) | 2127 (79.5) | -0.95 | 54 (77.1) | -0.88 | 11 (84.6) | -1.11 | 305 (79.6) | -0.95 | 304 (75.2) | -0.83 | 655 (83.5) | 1.11 |
| Urgent care encounter | 1016 (1.5) | 5 (0.2) | 0.15 | 0 (0.0) | 0.18 | 0 (0.0) | 0.18 | 1 (0.3) | 0.14 | 5 (1.2) | 0.03 | 2 (0.3) | 0.14 |