Table 4. Cohort characteristics before propensity score matching (PSM), reflecting differing percentages of characteristics (conditions, and outcome of death) with standardized mean differences (SMD) for those prescribed a specific statin compared to the control cohort not treated with a statin.
| Characteristic | No Statins | Atorvastatin | SMD | Lovastatin | SMD | Pitavastatin | SMD | Pravastatin | SMD | Rosuvastatin | SMD | Simvastatin | SMD |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | 65978 | 2676 | 70 | 13 | 383 | 404 | 784 | ||||||
| Condition (%) | |||||||||||||
| Obese | 23567 (35.7) | 1151 (43.0) | -0.15 | 24 (34.3) | 0.03 | 2 (15.4) | 0.48 | 157 (41.0) | -0.11 | 170 (42.1) | -0.13 | 298 (38.0) | -0.05 |
| Cancer | 2664 (4.0) | 188 (7.0) | -0.13 | 3 (4.3) | -0.01 | 1 (7.7) | -0.16 | 30 (7.8) | -0.16 | 25 (6.2) | -0.10 | 49 (6.2) | -0.10 |
| Cerebrovascular Disease | 2311 (3.5) | 378 (14.1) | 0.38 | 8 (11.4) | 0.31 | 2 (15.4) | 0.42 | 51 (13.3) | 0.36 | 60 (14.9) | 0.40 | 91 (11.6) | 0.31 |
| Chronic Kidney Disease (CKD) | 4650 (7.0) | 654 (24.4) | 0.49 | 10 (14.3) | 0.24 | 4 (30.8) | 0.64 | 121 (31.6) | 0.65 | 86 (21.3) | 0.42 | 178 (22.7) | 0.45 |
| COPD | 3460 (5.2) | 386 (14.4) | 0.31 | 7 (10.0) | 0.18 | 2 (15.4) | 0.34 | 60 (15.7) | 0.35 | 40 (9.9) | -0.18 | 113 (14.4) | 0.31 |
| Diabetes | 13677 (20.7) | 1586 (59.3) | -0.86 | 44 (62.9) | -0.95 | 8 (61.5) | -0.91 | 246 (64.2) | -0.98 | 232 (57.4) | -0.81 | 464 (59.2) | -0.85 |
| Heart Diseases | 7141 (10.8) | 1029 (38.5) | -0.68 | 22 (31.4) | -0.52 | 4 (30.8) | -0.51 | 154 (40.2) | -0.72 | 164 (40.6) | -0.73 | 280 (35.7) | -0.62 |
| Hypertension | 23146 (35.1) | 2206 (82.4) | -1.10 | 57 (81.4) | -1.07 | 11 (84.6) | -1.17 | 339 (88.5) | -1.32 | 337 (83.4) | -1.13 | 649 (82.8) | -1.11 |
| High Cholesterol | 9302 (14.1) | 1932 (72.2) | -1.45 | 57 (81.4) | -1.83 | 11 (84.6) | -1.99 | 304 (79.4) | -1.73 | 312 (77.2) | -1.64 | 592 (75.5) | -1.57 |
| Outcome (%) | |||||||||||||
| Mortality | 4235 (6.4) | 431 (16.1) | 0.31 | 15 (21.4) | 0.44 | 4 (30.8) | 0.66 | 71 (18.5) | 0.37 | 53 (13.1) | 0.23 | 153 (19.5) | 0.40 |
| Healthcare Center Type (%) | |||||||||||||
| Academic | 5689 (8.6) | 254 (9.5) | -0.03 | 4 (5.7) | 0.11 | 0 (0.0) | 0.43 | 46 (12.0) | 0.11 | 30 (7.4) | 0.04 | 60 (7.7) | 0.04 |
| Children | 263 (0.4) | 0 (0.0) | 0.09 | 0 (0.0) | 0.09 | 0 (0.0) | 0.09 | 0 (0.0) | 0.09 | 0 (0.0) | 0.09 | 0 (0.0) | 0.09 |
| Community Healthcare | 161 (0.2) | 6 (0.2) | 0.00 | 0 (0.0) | 0.07 | 0 (0.0) | 0.07 | 0 (0.0) | 0.07 | 0 (0.0) | 0.07 | 1 (0.1) | 0.03 |
| Community Hospital | 401 (0.6) | 13 (0.5) | 0.02 | 0 (0.0) | 0.11 | 0 (0.0) | 0.11 | 6 (1.6) | -0.09 | 3 (0.7) | -0.02 | 11 (1.4) | -0.08 |
| Critical Access | 39 (0.1) | 0 (0.0) | 0.03 | 0 (0.0) | 0.03 | 0 (0.0) | 0.03 | 0 (0.0) | 0.03 | 0 (0.0) | 0.03 | 0 (0.0) | 0.03 |
| IDN | 51485 (78.0) | 2108 (78.8) | -0.02 | 56 (80.0) | -0.05 | 10 (76.9) | 0.03 | 280 (73.1) | 0.12 | 309 (76.5) | 0.04 | 607 (77.4) | 0.02 |
| Regional Hospital | 7940 (12.0) | 295 (11.0) | 0.03 | 10 (14.3) | -0.07 | 3 (23.1) | -0.29 | 51 (13.3) | -0.04 | 62 (15.3) | -0.10 | 105 (13.4) | -0.04 |
| Region (%) | |||||||||||||
| Northeast | 14216 (21.5) | 656 (24.5) | -0.07 | 11 (15.7) | 0.15 | 2 (15.4) | 0.16 | 61 (15.9) | 0.14 | 58 (14.4) | 0.19 | 162 (20.7) | 0.02 |
| Midwest | 5196 (7.9) | 207 (7.7) | 0.01 | 3 (4.3) | 0.15 | 0 (0.0) | 0.41 | 29 (7.6) | 0.01 | 24 (5.9) | 0.08 | 53 (6.8) | 0.04 |
| South | 26143 (39.6) | 1012 (37.8) | 0.04 | 23 (32.9) | 0.14 | 9 (69.2) | -0.62 | 194 (50.7) | -0.22 | 227 (56.2) | -0.34 | 289 (36.9) | 0.06 |
| West | 20423 (31.0) | 801 (29.9) | 0.02 | 33 (47.1) | -0.34 | 2 (15.4) | 0.38 | 99 (25.8) | 0.11 | 95 (23.5) | 0.17 | 280 (35.7) | -0.10 |