Table 5. Mortality rates of patients treated with (A) atorvastatin, (B) lovastatin, (C) pravastatin, (D) rosuvastatin, and (E) simvastatin, and matched control groups, and relative risk of death with 95% confidence interval and Benjamini-Hochberg adjusted p-value from the iteration with the least significant result for each comparison.
treated patients | controls | |||||
---|---|---|---|---|---|---|
Statin (moderate dose) | Mortality rate, % | No. died/No. treated | Mortality rate, % | No. died/No. treated | Relative risk (95% CI) | Adjusted P-value* |
Atorvastatin | 16.1 | 431/2676 | 20.4 | 545/2676 | 0.86 (0.80–0.93) | 6.24E-05 |
Lovastatin | 21.4 | 15/70 | 19.1 | 134/700 | 1.14 (0.66–1.96) | 0.76 |
Pravastatin | 18.5 | 71/383 | 23.1 | 883/3830 | 0.78 (0.61–1.00) | 0.05 |
Rosuvastatin | 13.1 | 53/404 | 21.0 | 850/4040 | 0.59 (0.45–0.78) | 9.61E-05 |
Simvastatin | 19.5 | 153/784 | 23.3 | 914/3920 | 0.83 (0.70–0.97) | 0.02 |