Table I.
Characteristics of the studies assessed for eligibility.
| Study design | Index test | References standard | Study assessment | |
|---|---|---|---|---|
| Goldberg 1982 | Prospective cohort study | Vabra & Accurette | Blind D&C | Excluded |
| Henig 1989 | RCT | Pipelle | Novak | Excluded |
| Batool 1994 | Prospective cohort study | Pipelle | Blind D&C | Excluded |
| Ben-baruch 1994 | Retrospective cohort study | Pipelle | Blind D&C | Excluded |
| Van den Bosch 1995 | Prospective cohort study | Pipelle | Hysteroscopy w/histology | Excluded |
| Van den Bosch 1996 | Prospective cohort study | Pipelle | Hysteroscopy w/histology | Excluded |
| Giusa-Chifieri 1996 | Prospective cohort study | Novak | Hysteroscopy w/histology | Excluded |
| Gupta 1996 | Prospective cohort study | Pipelle | Hysteroscopy w/histology | Excluded |
| De Silva 1997 | Prospective cohort study | Pipelle | Hysteroscopy w/histology | Excluded |
| Mortakis 1997 | Not reported | Pipelle | Hysteroscopy w/histology | Excluded |
| Tahir 1999 | RCT | Inpatient hysteroscopy & D&C | Outpatient Pipelle ± TVU ± hysteroscopy | Excluded |
| Cooper 2000 | Review | Directed biopsy with hysteroscopy | - | Excluded |
| Bunyavejchevin 2001 | Prospective cohort study | Pipelle | Blind D&C | Excluded |
| Epstein 2001 | Prospective cohort study | Endorette | Blind D&C | Excluded |
| Ceci 2002 | Retrospective cohort study | Hysteroscopy | D&C* | Included |
| Critchley 2004 | RCT | Pipelle | Tao Brush | Excluded |
| Spicer 2006 | Prospective cohort study | Accurette | Hysteroscopy w/histology | Excluded |
| Polena 2007 | Prospective sequential cohort study | Pipelle Mark 2 | Pipelle Mark 2 ± hysteroscopy | Excluded |
| Rauf 2014 | RCT | Pipelle | D&C | Excluded |
| Liu 2015 | Prospective sequential cohort study | Pipelle | D&C | Excluded |
| Wanderley 2016 | Cross-sectional study | Hysteroscopy | D&C | Included |
| Rosenblatt 2017 | Prospective pilot study | MyoSure Lite hysteroscopic tissue removal system | D&C | Included |
| Li 2017 | Prospective cohort study | SAP-1 sampler device followed by hysteroscopy (169) | SAP-1 sampler device followed by D&C (13) | Excluded |
| Yela 2018 | Retrospective cohort study | TVU | Hysteroscopy | Excluded |
| Di Spiezio Sardo 2020 | Retrospective cohort study | D&C | Hysteroscopy | Included |
D&C, dilation, and curettage; RCT, randomised clinical trial; TVU, transvaginal ultrasound; *Control group was from Bettocchi et al. 2001 (37).