Table 2.
Oncologic and Treatment Data
| Variable | Surgery alone (n = 392) | Adjuvant chemotherapy only (n = 291) | Adjuvant chemoradiation (n = 447) | p Value |
|---|---|---|---|---|
| Tumor size, cm, mean ± SD | 2.9 ± 1.4 | 3.3 ± 2.1 | 3.1 ± 1.3 | 0.01 |
| Tumor grade, n (%)* | 0.61 | |||
| 1 | 38 (11) | 38 (13) | 41 (9) | |
| 2 | 219 (63) | 175 (61) | 276 (63) | |
| 3 | 90 (26) | 76 (26) | 120 (28) | |
| Tumor stage, n (%) | 0.03 | |||
| I | 57 (15) | 21 (7) | 63 (14) | |
| II | 333 (85) | 268 (92) | 380 (85) | |
| III | 2 (0.5) | 2 (1) | 4 (1) | |
| Lymph nodes, positive, n (%) | 166 (42) | 203 (70) | 261 (58) | <0.001† |
| Vein resection, yes, n (%) | 44 (11) | 50 (17) | 70 (16) | 0.062 |
| Margin positive, yes, n (%) | 64 (16) | 61 (21) | 124 (28) | <0.001‡ |
| Lymph nodes resected, median (IQR) | 14 (8, 21) | 18 (11, 27) | 15 (9, 22) | <0.001 |
| Blood transfusion, yes, n (%) | 114 (29) | 75 (26) | 126 (28) | 0.623 |
| Length of stay, d, median (IQR) | 11 (8, 18) | 9 (7, 13) | 9 (7,12) | <0.001 |
*
Grade 1, well differentiated; 2, moderately differentiated; 3, poorly differentiated.
†
p < 0.001, surgery alone vs adjuvant chemotherapy and adjuvant chemoradiation; p = 0.001, adjuvant chemotherapy vs adjuvant chemoradiation.
‡
p = 0.12, surgery alone vs adjuvant chemotherapy; p < 0.001, surgery alone vs adjuvant chemoradiation; p = 0.03 adjuvant chemotherapy vs adjuvant chemoradiation. IQR, interquartile range.