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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Cancer Cytopathol. 2022 Mar 4;130(6):423–432. doi: 10.1002/cncy.22564

TABLE 2.

Reporting Rates and Risk of Malignancies of Diagnostic Categories

Diagnostic Category No. (%) Histology Risk of Malignancy (%) Malignant Tumors on Histology

I. UNSAT 35 (7.4) 10 30 1 metastatic dedifferentiated liposarcoma, 1 metastatic clear cell RCC, 1 metastatic leiomyosarcoma
II. NN 12 (2.5) 1 0 N/A
III. BACE 103 (21.8) 21 0 N/A
IV. NONC 10 (2.1) 6 0 N/A
V. AUS 31 (6.6) 21 47.6 4 adrenal cortical carcinoma, 2 metastatic clear cell RCC, 2 metastatic adenocarcinoma of the lung, 1 metastatic leiomyosarcoma, 1 posttransplant lymphoproliférative disorder
VI. SM 10 (2.1) 6 100 3 diffuse large B-cell lymphoma, 1 metastatic adenocarcinoma of the pancreas, 1 metastatic clear cell RCC, 1 adrenal cortical carcinoma
VII. MAL 272 (57.5) 88 98.9 See Table 3

Abbreviations: AUS, atypia of undetermined significance; BACE, benign adrenal cortical elements; MAL, malignant; NN, nonneoplastic; NONC, primary neoplasm of noncortical origin; RCC, renal cell carcinoma; SM, suspicious for malignancy; UNSAT, nondiagnostic.