Correlation of chromatin remodeling gene (CRG) alterations in endometrial carcinomas with histopathologic features. (A) Bar-plot showing the distribution of myometrial invasion among CRG-altered and CRG-wild-type uterine endometrioid carcinomas. (B) Bar-plot showing the distribution of lymphovascular invasion among CRG-altered and CRG-wild-type uterine endometrioid carcinomas. (C) Box and whisker plots comparing the depth of myometrial invasion between CRG-altered and CRG-wild-type endometrial carcinomas among the four molecular subtypes of endometrial carcinoma.
UEC, Uterine endometrioid carcinoma; POLE, POLE exonuclease domain mutated carcinoma; MSI-H, DNA mismatch repair deficient carcinoma; CN-L, TP53 wild-type non-hypermutant endometrial carcinomas; CN-H, TP53 altered non-hypermutant endometrial carcinomas.