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. Author manuscript; available in PMC: 2024 Jun 1.
Published in final edited form as: J Immunol. 2023 Jun 1;210(11):1740–1751. doi: 10.4049/jimmunol.2300061

Figure 6: NME increases B cell activation.

Figure 6:

Number and frequency of (A) mature activated, (B) naïve, (C) class-switched, (D) and immature B cells in the lymph node harvested from SPF (black) and NME (green) offspring at 2, 3, or 6 weeks of age. (E) Lymph node B cell composition. (F) Number and frequency of plasma cells in the lymph node. 10-15 mice/group/time point. Data were collected from three individual experiments per group per age over two years. Example flow plots are from a 6-week-old NME mouse. (G) Total IgG concentration (ng/mL) in the plasma of 3-week-old SPF and NME mice measured by a single ELISA, samples were assayed in duplicate. 3-4 mice/group. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001.