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. Author manuscript; available in PMC: 2024 Jun 1.
Published in final edited form as: J Immunol. 2023 Jun 1;210(11):1740–1751. doi: 10.4049/jimmunol.2300061

Figure 8: NME enhances cytokine, PRR expression, and host defense.

Figure 8:

(A) Cytokine and chemokine levels in plasma harvested from 3-week-old SPF (solid black line), 3-week-old NME (solid green line), 6-week-old SPF (dotted black line), and 6-week-old NME (dotted green line) mice. Data depicts the average of 13 mice and two experimental replicates. (B) qPCR analysis of TLRs, MyD88, and CD14 in adherent myeloid cells isolated from spleens of SPF (n = 4) and NME (n = 8) mice. Data are representative of 2 technical replicates. (C) LM CFU in spleen 4 days post inoculation in SPF (black) and NME (green) mice. 9 mice/group were analyzed, representative of 2 technical replicates. †p < 0.05, *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001.