Table 1.
References, divided by species, for the role of IGF2 in neuronal plasticity, memory formation and enhancement (top) and for effects of IGF2 in aging, neural diseases, and other effects (bottom)
| CONDITION OR DISEASE | REFERENCES | |||
|---|---|---|---|---|
| Species | ||||
| Human | Rat | Mouse | Chick | |
| Memory Formation and Enhancement | [27, 32, 35, 37] | [28, 32, 34, 36] | ||
| Plasticity | [38] | |||
| Aging | [39, 48] | |||
| Neurodevelopmental Disorders | [40, 41, 49] | |||
| Huntington Disease | [51] | [50, 51] | ||
| Alzheimer’s disease | [45, 51, 52, 55, 57–59] | [54, 56, 57, 60] | ||
| Parkinson Disease | [62] | [61, 62] | ||
| Schizophrenia | [63, 64] | |||
| Stroke | [66] | [65] | ||
| Repair from Stress | [67, 68] | |||
| Traumatic Brain Injury or Hemorrhagic Brain Damage | [65, 69, 70] | |||
| Depression | [71, 72] | |||
| Amyotrophic Lateral Sclerosis | [73, 74] | [74] | [73, 74] | |
| Motor Neuron Regeneration | [75, 76] | |||
| Neuroprotection | [67, 77, 78] | |||
| Psychiatric and Neurological Disorders | [5] | [5] | [5] | |
| Lack of effect in Angelman syndrome | [79] | [79] | ||
| Lack of effect on cognitive impairment following TBI | [80] | |||
| Brain metastasis formation in breast cancer | [81] | [81] | ||
| Food intake | [82] | [83] | ||