Table 5.

Literature review of transfused fetuses with parvovirus B 19 infection [6, 8, 13–16, 27–37, 39]

Study (first author)	Transfused case	GA at first transfusion (weeks of gestation)		Hydrops	Cases with severe thrombocytopenia	Survival rate (%; n)
		< 20 + 0	≥ 20 + 0
Smoleniec, 1994 [15]	5	1	4	5	1	60 (3/5)
Fairley, 1995 [27]	12	n.a	n.a	7	n.a	75 (9/12)
Cameron, 1997 [28]	3	0	3	3	n.a	33 (1/3)
Odibo, 1998 [29]	3	1	2	3	n.a	100 (3/3)
Rodis, 1998 [30]a	164	n.a. (18–32)	n.a	137	n.a	83.5 (137/164)
Forestier, 1999 [31]	7	1	6	7	2	85.7 (6/7)
Schild, 1999 [14]	30	3	27	30	11	80 (24/30)
Enders, 2004 [8]	16	n.a	n.a	16	n.a	87.5 (14/16)
Segata, 2007 [6]	11	3	8	8	7	72.7 (8/11)
De Haan, 2008 [37]	30	2	28	30	14	77 (23/30)
Simms, 2009 [13]	8	n.a. (18–27)	n.a	8	2	62.5 (5/8)
Chauvet, 2011 [32]	19	n.a	n.a	19	n.a	47 (11/19)
Garabedian, 2014 [33]	13	0	13	5	n.a	76.9 (10/13)
Macé, 2014 [16]	17	0	17	17	9	76 (13/17)
Melamed, 2015 [35]	29	4	25	25	11	75.9 (22/29)
Mackie, 2015 [34]	5	2	3	5	2	60 (3/5)
Zavattoni, 2016 [36]	9	0	9	9	n.a	66.7 (6/9)
Sanchéz-Durán, 2020 [39]	10	n.a	n.a	8	n.a	80 (8/10)
Current Studyb	103	57	46	44	17	84.5 (87/103)
Total	494	74/265c	191/265c	386/494	76	79.5 (393/494)

GA gestational age, n.a. not available

^aMulticenter survey

^b55 cases were previously published [17]

^cThe timing of the first IUT could be classified as < 20 and ≥ 20 weeks of gestation in 265 of the 494 cases