Table 3.

Cox proportional hazards regression for the association between time of day and CVD mortality stratified by chronotypes. ^*

	Midday Group (Reference)	Early Morning Group	Late Morning Group	Night Group
Morning-Type Individuals (n=53,328)
No. of Deaths	87	79	143	61
No. of Participants	13,074	13,257	17,043	9,954
Hazard Ratio	1 (Reference)	1.30 (0.95 – 1.77)	1.13 (0.87 – 1.48)	1.52 (1.09 – 2.11)
Evening-Type Individuals (n=30,962)
No. of Deaths	70	25	45	52
No. of Participants	11,542	3,554	5,887	9,979
Hazard Ratio	1 (Reference)	2.17 (1.36 – 3.48)	1.23 (0.85 – 1.80)	1.37 (0.95 – 1.98)

^*Adjusted for physical activity volume, age, sex, ethnicity, Townsend Deprivation Index, body-mass index, smoking, alcohol intake, healthy eating score, a family history of heart disease and stroke, hypertension, high cholesterol, diabetes, long-standing illness, a personal history of heart attack, angina, and stroke, and general health status.