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Controlling subcellular localization. (A) ER-targeted delivery of phototherapy agents or oxygen-delivering hemoglobin is achieved using the pardaxin peptide (FAL). Adapted with permission.[162] Copyright 2019, Nature Publishing Group. (B) Mitochondria-targeted delivery of the photosensitizer Ce6 and a CRISPR-Cas9 plasmid against Ptpn2 is achieved using the targeting ligand triphenylphosphonium (TPP). Adapted with permission.[168] Copyright 2020, Elsevier Ltd.
