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. 2023 May 4;15:1121190. doi: 10.3389/fnagi.2023.1121190

Table 4.

Hazard ratios of depression and low global cognition for all-cause mortality, cardiovascular mortality and cancer mortality.

Mortality Depression Low global cognition The interaction effect
HR (95% CI) P HR (95% CI) P HR (95% CI) P
All-cause mortality 1.39 (0.80, 2.41) 0.237 1.76 (1.31, 2.35) <0.001 2.18 (0.73, 6.49) 0.156
Cardiovascular mortality 1.89 (0.94, 3.79) 0.073 1.95 (1.17, 3.24) 0.012 4.35 (1.09, 17.25) 0.037
Cancer mortality 0.74 (0.28, 1.96) 0.536 1.27 (0.64, 2.51) 0.476 1.39 (0.26, 7.27) 0.690

Adjusted for age categories, gender, race, marital status, education, smoke, alcohol drinking, physical activity, ratio of family income to poverty category, body mass index category, coronary heart disease, diabetes, hypertension, stroke and cancer.

HR, hazard ratio; CI, confidence interval.