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. 2023 Apr 23;26(5):106723. doi: 10.1016/j.isci.2023.106723

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© 2023 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Stabilization of F-actin does not disrupt normal regulation of synaptic CaMKII accumulation

Scale bars, 5 μm.

(A and B) (A) cLTP stimulation results in the synaptic accumulation of CaMKII (n = 14 neurons; ∗∗p < 0.01; paired two-tailed t-test), which was unaffected by (B) jasplakinolide (n = 16 neurons; ∗∗∗p < 0.001; paired two-tailed t-test).

(C) cLTD stimulation after pre-treatment with jasplakinolide does not result in CaMKII synaptic accumulation (n = 16 neurons; paired two-tailed t-test).