Figure 1.

(A) Physical setup of patients on the MRgFUS system with the FUS system integrated into the bed. Patients may lay on the bed as per the required orientation with the target region of interest positioned over top of the FUS transducer. (B) The FUS system is integrated into the MRI bed. The concave transducer is submerged in degassed, deionized water with a coupling gel pad to allow for the acoustic beams to traverse into the patient with minimal energy loss. The multielement transducer is capable of focusing ultrasound waves to a targeted focal region which can generate heat and induce physical damage to the targeted tissue. All of this is done while the patient is inside the MRI after thorough planning of the treatment.

Abbreviations: FUS, focused ultrasound; MRI, magnetic resonance imaging; MRgFUS, MRI-guided focused ultrasound.