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. 2023 May 4;14:1166609. doi: 10.3389/fimmu.2023.1166609

Figure 2.

Figure 2

Nicotinamide riboside (NR) treatment has no apparent effect on sociability in C57BL6 (BL6) and CD157KO male mice in the three-chamber test. Duration spent in the chamber with Stranger 1 mouse in a cage (Str1) or a non-social target (object) by wild-type (BL6; A) or CD157KO (B) mice. (C, D) Duration spent in the chamber with Stranger 1 mouse in a cage (Str1) or a non-social target (object) by wild-type (BL6; C) or CD157KO (D) mice, which were treated with gavage administration of saline (PL) or nicotinamide riboside (NR) for 12 days and then examined. Two-tailed Student’s t-test, **P < 0.01, ***P < 0.001, ****P < 0.0001.