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. 2023 May 4;14:1166609. doi: 10.3389/fimmu.2023.1166609

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Copyright © 2023 Gerasimenko and Higashida

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Social memory behavior in wild-type (ICR) and CD38KO mice and no or little effect of nicotinamide riboside (NR) treatment. Duration spent in the chamber with the familiar mouse in a cage (Str1) or a novel mouse (Str3) by ICR (A, C) or CD38KO (B, D) mice. Mice were treated with gavage administration of saline (PL) or NR for 12 days (C, D) or were without any treatment (A, B). Note that social memory behavior was observed in ICR mice (A, C) but was not affected by NR treatment (C). Two-tailed Student’s t-test, *P < 0.05.