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. 2023 May 4;14:1136308. doi: 10.3389/fimmu.2023.1136308

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Copyright © 2023 del Pino Molina, Bravo Gallego, Nozal, Soto-Serrano, Martínez-Feito, Reche-Yebra, González-Torbay, Cuesta-Martín de la Cámara, Gianelli, Cámara, González-García, González-Muñoz, Rodríguez-Pena and López Granados

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Analysis of specific RBD⁺ IgG⁺ MBCs. (A): Percentage of specific RBD⁺ IgG⁺ MBCs (within total IgG⁺ MBC) prior to vaccination and 21 days after the second dose in healthy healthcare workers (HD) and patients with inborn errors of immunity (IEI). In red, HD with previous natural SARS-CoV-2 infection; in blue, non-infected HD; in orange, patients with previous natural SARS-CoV-2 infection; and in green, patients non-previously infected, prior to vaccination, and 21 days after the second dose. (B): Percentage of specific RBD⁺ IgG⁺ MBCs (within total IgG⁺ MBCs) 21 days after the second dose, in healthcare workers (HD) and in patients with IEI classified in different IEI categories. ****<0.0001.