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. 2023 Apr 24;73:101723. doi: 10.1016/j.molmet.2023.101723

Figure 3.

Figure 3

Brain Insulin requires the MAPK signaling pathway in the MBH in order to suppress WAT lipolysis. (A) Study protocol (B) Ra glycerol measured in plasma at baseline (TP 120) and at the end of the 1 mU · kg−1 · min−1 insulin clamp (TP 240). (C) Representative western blot and (D) quantification of HSL activation state and total expression in epidydimal WAT samples harvested at the end of a 1mU clamp. Data are shown as mean ± SEM, ∗p < 0.05, ∗∗p < 0.01 by Student's unpaired t test, n ≥ 4 per group.