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. 2023 May 16;13(5):e067643. doi: 10.1136/bmjopen-2022-067643

Table 5.

Association between cardiometabolic risk factors and specific target organ damage (CKD)

CKD
Variable Total no (%) Yes no (%) No (%) OR (95% CI) Model 1 Model 2
Overweight/obese
 No 1598 (66.8) 168 (10.5) 1430 (89.5) Ref.
 Yes 796 (33.2) 106 (13.3) 690 (86.7) 0.750 (0.578 to 0.974) 0.774 (0.596–1.005) 0.778 (0.589–1.028)
Alcohol
 No 1486 (62.1) 172 (11.6) 1314 (88.4) Ref.
 Yes 908 (37.9) 102 (11.2) 1844 (89.0) 1.003 (0.772 to 1.303) 0.915 (0.688–1.218) 0.810 (0.565–1.161)
Smoking
 No 2073 (86.6) 229 (11.0) 1844 (89.0) Ref.
 Yes 321 (13.4) 45 (14.0) 276 (86.0) 0.784 (0.554 to 1.111) 0.678 (0.448–1.024) 0.665 (0.439–1.008)
Diabetes
 No 2187 (91.7) 254 (11.6) 1933 (88.4) Ref.
 Yes 199 (8.3) 19 (9.5) 180 (90.5) 1.212 (0.741 to 1.983) 1.200 (0.730–1.975) 1.208 (0.730–1.997)
Hypertension
 No 1550 (64.7) 186 (12.0) 1364 (88.0) Ref.
 Yes 844 (35.3) 88 (10.4) 756 (89.6) 1.163 (0.887 to 1.525) 1.126 (0.852–1.486) 1.118 (0.843–1.483)
Waist circumference
 Normal 1882 (78.6) 213 (11.3) 1669 (88.7) Ref.
 Abnormal 512 (21.4) 61 (11.9) 451 (88.1) 0.926 (0.683 to 1.254) 0.870 (0.634–1.193) 0.825 (0.598–1.139)
Total cholesterol
 Normal 2163 (90.4) 247 (11.4) 1916 (88.6) Ref.
 Abnormal 231 (9.6) 27 (11.7) 204 (88.3) 1.170 (0.663 to 2.066) 0.876 (0.566–1.356) 0.862 (0.555–1.339)
LDL-C
 Normal 2077 (86.8) 239 (11.5) 1838 (88.5) Ref.
 High 317 (13.2) 35 (11.0) 282 (89.2) 1.355 (0.754 to 2.433) 1.000 (0.682–1.465) 0.951 (0.641–1.409)
Low HDL-C
 No 1986 (82.9) 235 (11.8) 1751 (88.2) Ref.
 Yes 409 (17.1) 39 (9.5) 370 (90.5) 1.261 (0.881 to 1.804) 1.277 (0.893–1.827) 1.275 (0.890–1.825)
Dyslipidaemia
 No 1882 (78.6) 213 (11.3) 1669 (88.7) Ref.
 Yes 512 (21.4) 61 (11.9) 451 (88.1) 0.706 (0.399 to 1.252) 0.870 (0.634–1.193) 0.825 (0.598–1.139)

CKD, chronic kidney disease; HDL, high-density lipoprotein; LDL, low-density lipoprotein.