FIG. 3.

Amino acid sequence deduced from the nucleotide sequence of the MPR1 gene (MPR1) and its alignment with S. cerevisiae Spt10p (SPT10) and the S. pombe hypothetical 23.8-kDa protein (S. pombe). Numbers above the sequences refer to the MPR1 gene. An amino acid residue at position 85 in the MPR1 gene product (Gly for the MPR1 gene product and Glu for the MPR2 gene product) is boxed. Amino acids with identity or similarity are shown in shaded boxes. A horizontal line indicates the absence of the corresponding amino acid residue at this position. Filled dots under the sequences indicate the highly conserved positions in consensus motifs (A to D) of the N-acetyltransferase superfamily (23). The GenBank accession numbers for S. cerevisiae Spt10p and the S. pombe hypothetical 23.8-kDa protein are L24435 and Z67999, respectively.