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. Author manuscript; available in PMC: 2023 May 18.
Published in final edited form as: Immunohorizons. 2022 May 20;6(5):299–306. doi: 10.4049/immunohorizons.2200013

Figure 2. Bat RBCs contain DNA and RNA and bind pathogen derived RNA.

Figure 2.

(A) 16S rDNA gene copies associated with RBCs derived from healthy human donors and bats. (B) 18S rRNA content of bat and human RBCs. For (A and B), each dot represents an individual bat or human donor sample,****p<0.0001. (C) qPCR quantitation for ZIKV RNA on RBCs incubated with varying concentrations of ZIKV RNA with PCR of the envelope (E) and non-structural protein 5 (NS5) genes. (D) qPCR for SARS-CoV-2 RNA on RBCs incubated with varying concentrations of SARS-CoV-2 RNA with PCR for two different amplicons for nucleocapsid gene (N1 and N2). n=1 bat. For (C and D), technical replicates are shown for each dose of RNA used. **P<0.01, ****p<0001.