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. Author manuscript; available in PMC: 2023 May 18.
Published in final edited form as: NEJM Evid. 2022 Jan 10;1(3):10.1056/evidoa2100057. doi: 10.1056/evidoa2100057

Table 1.

Characteristics of Fully Vaccinated Persons and Covid-19 Cases and Deaths for 15 U.S. Jurisdictions, from January 3 to September 4, 2021

Covid-19 cases Covid-19 deaths
Characteristic No. of total vaccinated for 15 jurisdictions No. of cases Case rate per 100,000 person-wk* No. of total vaccinated for 14 jurisdictions No. ofdeaths Death rate per 100,000 person-wk*
Overall 48,832,299 411,661 46.7 (46.6–46.9) 45,988,351 6322 0.76 (0.75–0.78)
Age — yr
 12–17 2,253,130 8974 39.3 (38.5–40.1) 2,119,998 1 0 (0–0.03)
 18–49 20,022,549 189,269 57.5 (57.2–57.7) 18,907,371 134 0.04 (0.04–0.05)
 50–64 12,853,359 103,496 44.9 (44.6–45.2) 12,099,120 741 0.34 (0.32–0.37)
 65–79 10,614,732 80,666 35.4 (35.1–35.6) 9,971,402 2371 1.11 (1.06–1.15)
 ≥80 3,088,529 29,256 41.9 (41.4–42.4) 2,890,460 3075 4.71 (4.55–4.88)
Vaccine product
 BNT162b2 (Pfizer-BioNTech) 26,269,165 247,051 53.1 (52.9–53.3) 24,766,315 3701 0.85 (0.82–0.87)
 mRNA-1273 (Moderna) 18,686,366 113,724 32.4 (32.2–32.6) 17,575,605 1853 0.56 (0.54–0.59)
 Ad26. COV2.S (Janssen-Johnson & Johnson) 3,876,768 50,886 79.0 (78.3–79.7) 3,646,431 768 1.27 (1.18–1.36)
Vaccine product and recipient age — yr
 BNT162b2
  12–17 2,253,130 8974 39.3 (38.5–40.1) 2,119,998 1 0 (0–0.03)
  18–49 11,066,415 114,320 62.7 (62.4–63.1) 10,480,750 59 0.03 (0.03–0.04)
  50–64 6,570,353 59,439 50.0 (49.6–50.4) 6,196,382 334 0.30 (0.27–0.33)
  65–79 4,936,528 46,591 43.2 (42.8–43.6) 4,617,760 1307 1.30 (1.23–1.37)
  ≥80 1,442,739 17,727 52.8 (52.1–53.6) 1,351,425 2000 6.36 (6.08–6.64)
 mRNA-1273
  18–49 6,901,002 47,468 41.3 (41.0–41.7) 6,495,495 41 0.04 (0.03–0.05)
  50–64 5,077,105 27,701 30.6 (30.2–30.9) 4,779,322 211 0.25 (0.22–0.28)
  65–79 5,189,360 28,523 25.6 (25.3–25.9) 4,884,325 745 0.71 (0.66–0.76)
  ≥80 1,518,899 10,032 29.6 (29.0–30.1) 1,416,463 856 2.71 (2.53–2.90)
 Ad26.COV2.S
  18–49 2,055,132 27,481 85.3 (84.3–86.3) 1,931,126 34 0.11 (0.08–0.16)
  50–64 1,205,901 16,356 77.6 (76.5–78.8) 1,123,416 196 1.00 (0.87–1.15)
  65–79 488,844 5552 62.6 (61.0–64.3) 469,317 319 3.74 (3.35–4.17)
  ≥80 126,891 1497 65.2 (62.0–68.6) 122,572 219 9.86 (8.63–11.25)
Vaccination cohort
 January to February 8,366,983 114,195 50.1 (49.8–50.4) 7,863,667 2692 1.26 (1.21–1.3)
 March to April 24,331,245 216,897 46.0 (45.8–46.2) 22,755,728 3035 0.69 (0.66–0.71)
 May to June 13,565,104 72,812 43.2 (42.9–43.5) 12,905,249 524 0.33 (0.30–0.36)
 July 2,568,967 7757 58.9 (57.6–60.2) 2,463,707 71 0.56 (0.45–0.71)
Region
 South 17,665,391 212,064 66.3 (66.0–66.6) 17,665,391 4396 1.37 (1.33–1.42)
 West 6,201,697 48,334 42.2 (41.8–42.6) 6,201,697 436 0.38 (0.35–0.42)
 Northeast 13,657,121 74,163 31.4 (31.1–31.6) 13,657,121 653 0.28 (0.26–0.30)
 Midwest 11,308,090 77,100 36.8 (36.5–37.0) 8,464,142 837 0.53 (0.50–0.57)
*

Rates are calculated using person-weeks as the denominator, and 95% confidence intervals are provided in parentheses. The widths of the intervals have not been adjusted for multiplicity and any of the inferences drawn may not be reproducible. Wisconsin did not contribute deaths due to lack of linkage between vital records and COVID-19 case surveillance.

Rates for counts fewer than 15 may be unstable and should be interpreted with caution.

Regions comprise the following jurisdictions: South (Arkansas, Georgia, Florida, and Tennessee), West (Arizona, Idaho, New Mexico, and Utah), Northeast (Massachusetts, New Jersey, and New York City), and Midwest (Indiana, Michigan, Nebraska, and Wisconsin).