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. Author manuscript; available in PMC: 2023 May 18.
Published in final edited form as: J Expo Sci Environ Epidemiol. 2020 Jan 27;31(2):366–376. doi: 10.1038/s41370-019-0192-8

Table 4.

Reverse-scale cox regression results and hazard ratios.

Parameter Dependent Not smoke exposed
Smoke exposed
Cox Beta P value Hazard Ratio per 1 SD Increase in CBC Cox Beta P value Hazard Ratio per 1 SD Increase in CBC
Eosinophils Benzene   0.449   0.0201 1.08 (1.01, 1.15) −0.012   0.9067 1.00 (0.97, 1.03)
Ethylbenzene   0.180   0.2171 1.03 (0.98, 1.08) −0.001   0.9912 1.00 (0.97, 1.03)
M-/p-Xylene   0.159   0.1512 1.03 (0.99, 1.06) −0.034   0.6948 0.99 (0.97, 1.02)
O-Xylene   0.108   0.5047 1.02 (0.97, 1.07) −0.050   0.6905 0.99 (0.95, 1.03)
1,4-Dichlorobenzene   0.048   0.7119 1.01 (0.97, 1.05) −0.176   0.5275 0.97 (0.89, 1.06)
Styrene   0.128   0.4905 1.02 (0.96, 1.09)   0.127   0.2198 1.02 (0.99, 1.06)
Toluene   0.013   0.9052 1.00 (0.97, 1.04) −0.011   0.9041 1.00 (0.97, 1.03)
Hematocrit Benzene   0.038   0.0194 1.16 (1.03, 1.31)   0.041   0.0014 1.18 (1.07, 1.3)
Ethylbenzene   0.026   0.0604 1.11 (1.00, 1.24)   0.035   0.0014 1.15 (1.06, 1.25)
M-/p-Xylene   0.021   0.0394 1.09 (1.00, 1.17)   0.042 <0.0001 1.18 (1.1, 1.26)
O-Xylene   0.015   0.2321 1.06 (0.96, 1.17)   0.042   0.0002 1.18 (1.09, 1.28)
1,4-Dichlorobenzene −0.012   0.2248 0.95 (0.89, 1.03) −0.017   0.1358 0.94 (0.86, 1.02)
Styrene   0.009   0.5441 1.04 (0.92, 1.16)   0.034   0.0118 1.14 (1.03, 1.27)
Toluene   0.018   0.0791 1.07 (0.99, 1.16)   0.033   0.0158 1.14 (1.03, 1.26)
Hemoglobin Benzene   0.077   0.0408 1.11 (1.00, 1.23)   0.140   0.0002 1.21 (1.1, 1.34)
Ethylbenzene   0.042   0.2513 1.06 (0.96, 1.17)   0.114   0.0004 1.17 (1.08, 1.27)
M-/p-Xylene   0.016   0.5014 1.02 (0.96, 1.09)   0.110   0.0002 1.16 (1.08, 1.26)
O-Xylene   0.011   0.7308 1.02 (0.93, 1.11)   0.114   0.0004 1.17 (1.08, 1.27)
1,4-Dichlorobenzene −0.041   0.1078 0.94 (0.88, 1.01) −0.056   0.0852 0.93 (0.85, 1.01)
Styrene   0.001   0.9585 1.00 (0.93, 1.08)   0.112   0.0035 1.17 (1.06, 1.29)
Toluene   0.023   0.3622 1.03 (0.96, 1.11)   0.119   0.0034 1.18 (1.06, 1.31)
Platelet count Benzene   0.002   0.0001 1.16 (1.08, 1.25)   0.001   0.0208 1.09 (1.01, 1.16)
Ethylbenzene   0.002 <0.0001 1.15 (1.09, 1.21)   0.001   0.1839 1.05 (0.98, 1.14)
M-/p-Xylene   0.001   0.0161 1.06 (1.01, 1.12)   0.001   0.1529 1.05 (0.98, 1.14)
O-Xylene   0.001   0.0016 1.10 (1.04, 1.17)   0.001   0.0890 1.07 (0.99, 1.16)
1,4-Dichlorobenzene −0.000   0.2539 0.97 (0.91, 1.02)   0.000   0.9792 1.00 (0.9, 1.11)
Styrene −0.000   0.7175 0.98 (0.88, 1.09)   0.001   0.2502 1.06 (0.96, 1.16)
Toluene   0.001   0.0030 1.09 (1.03, 1.15)   0.001   0.2040 1.06 (0.97, 1.15)
Red cell count Benzene   0.149   0.1421 1.07 (0.98, 1.18)   0.041   0.6560 1.02 (0.94, 1.11)
Ethylbenzene   0.035   0.6923 1.02 (0.94, 1.1)   0.027   0.7358 1.01 (0.94, 1.09)
M-/p-Xylene   0.019   0.7872 1.01 (0.94, 1.08)   0.088   0.1474 1.04 (0.99, 1.1)
O-Xylene   0.006   0.9387 1.00 (0.93, 1.08)   0.091   0.2295 1.04 (0.97, 1.12)
1,4-Dichlorobenzene −0.078   0.2478 0.96 (0.91, 1.03) −0.220   0.0228 0.90 (0.83, 0.99)
Styrene   0.004   0.9709 1.00 (0.9, 1.11)   0.052   0.5858 1.02 (0.94, 1.12)
Toluene   0.032   0.6228 1.02 (0.96, 1.08) −0.003   0.9742 1.00 (0.92, 1.09)
White cell count Benzene   0.017   0.1829 1.04 (0.98, 1.09)   0.081 <0.0001 1.19 (1.13, 1.25)
Ethylbenzene   0.010   0.4582 1.02 (0.97, 1.08)   0.076 <0.0001 1.18 (1.13, 1.23)
M-/p-Xylene   0.002   0.8341 1.01 (0.96, 1.06)   0.062 <0.0001 1.14 (1.09, 1.19)
O-Xylene   0.012   0.3433 1.03 (0.97, 1.08)   0.056 <0.0001 1.12 (1.07, 1.18)
1,4-Dichlorobenzene −0.001   0.9576 1.00 (0.94, 1.06) −0.009   0.6269 0.98 (0.91, 1.06)
Styrene   0.001   0.9354 1.00 (0.94, 1.07)   0.082 <0.0001 1.19 (1.17, 1.22)
Toluene −0.012   0.3134 0.98 (0.93, 1.02)   0.079 <0.0001 1.18 (1.14, 1.22)