Table 2.
Patient characteristics by survival status
| Clinical characteristics in the cohort of ALS cases | ||
|---|---|---|
| Site of onset, N (%) | ||
| Bulbar | 336 | 109 (32.4) |
| Spinal | 227 (67.6) | |
| Revised El Escorial criteria, N (%) | 336 | |
| Clinically suspected | 65 (19.4) | |
| Clinically possible | 34 (10.1) | |
| Clinically probable | 92 (27.4) | |
| Laboratorysupported, probable | 117 (34.8) | |
| Clinically definite | 28 (8.3) | |
| ALS-FRS-R, median (Q1, Q3) | 335 | 39.0 (34.0, 42.0) |
| Diagnostic delay (month), median (Q1, Q3) | 336 | 5.0 (2.6, 9.1) |
| Invasive ventilation, N (%) | 336 | 13 (3.9) |
| Pre-baseline ALS-FRS-R progression rate (points lost per month), median (IQR) | 335 | 0.9 (0.5–1.5) |
Characteristics of ALS cases (N = 335) with mortality follow-up by survival status
BMI body mass index, ALS-FRS-R ALS functional rating scale revised, HDL high-density lipoprotein, LDL low-density lipoprotein