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. Author manuscript; available in PMC: 2023 May 18.
Published in final edited form as: Science. 2023 Apr 28;380(6643):eabn3107. doi: 10.1126/science.abn3107

Fig. 5: Large-scale application of TOGA to hundreds of genomes.

Fig. 5:

(A) Human as reference. Left: Box plots with overlaid data points show the number of annotated orthologs. Non-placental mammals are highlighted with a yellow background. Right: Box plots showing evolutionary distances to human.

(B) Mouse as the reference. Muridae are shown as a separate group.

(C) TOGA with chicken as the reference, applied to 501 bird assemblies.

(D) TOGA for other species using NCBI RefSeq annotations (21) as the reference. BUSCO gene completeness of the reference annotation provides an upper bound for the completeness of TOGA’s query annotation.